Prophylactic Use of Urea-based Cream for Hand-foot Skin Reaction Associated with Sorafenib
نویسندگان
چکیده
منابع مشابه
Grade III hand-foot skin reaction induced by sorafenib*
1 Department of Dermatology, Apollonia University – Iasi, Romania. 2 Department of Dermatology, Institute of Macromolecular Chemistry “Petru Poni” – Iasi, Romania. 3 Department of Dermatology, Nicolina Medical Center – Iasi, Romania 4 Department of Surgery, University of Medicine and Pharmacy of Targu Mures – Mures, Romania. 5 Department of Cardiology, University of Medicine and Pharmacy of Tar...
متن کاملSorafenib (Nexavar®, BAY 43-9006)-induced Hand-foot Skin Reaction with Facial Erythema.
Sorafenib (Nexavar®, BAY 43-9006) is a novel, orally administered multi-kinase inhibitor that has recently been approved for the treatment of metastatic renal cell carcinoma. It is also used to delay disease progression in patients with advanced solid organ malignancies and metastatic melanoma. Sorafenib is associated with a relatively high incidence of dermatologic adverse events. The commonly...
متن کاملHand foot skin reaction in cancer patients treated with the multikinase inhibitors sorafenib and sunitinib.
BACKGROUND This study examined clinicopathological findings and management of hand foot skin reaction (HFSR) to sorafenib and sunitinib in a dermatology referral center for cancer-related toxic effects. PATIENTS AND METHODS We identified 12 patients who developed HFSR in a 1-year period (2007). Medical records and histological specimens were investigated for clinicopathological data and resul...
متن کاملHand-foot skin reaction increases with cumulative sorafenib dose and with combination anti-vascular endothelial growth factor therapy.
PURPOSE Sorafenib, a vascular endothelial growth factor (VEGF) receptor-2 and RAF kinase inhibitor, commonly causes skin toxicity. We retrospectively analyzed dermatologic toxicity in patients receiving combined antiangiogenic therapy involving sorafenib and bevacizumab. EXPERIMENTAL DESIGN Castration-resistant prostate cancer and metastatic non-small cell lung cancer patients were accrued to...
متن کاملDevelopment and validation of a prediction index for hand-foot skin reaction in cancer patients receiving sorafenib
BACKGROUND This study describes a repeated measures prediction index to identify patients at high risk of ≥grade 2 hand-foot skin reaction (HFSR) before each week of sorafenib therapy. METHODS Data from 451 patients who received a sorafenib (400 mg bid) as part of a clinical trial were reviewed (Escudier B, Eisen T, Stadler WM et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N En...
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ژورنال
عنوان ژورنال: Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)
سال: 2015
ISSN: 1346-342X,1882-1499
DOI: 10.5649/jjphcs.41.18